Cloning and characterization of a 77-kDa oestrogen receptor isolated from a human breast cancer cell line.

We have cloned and characterized a 77-kDa oestrogen receptor (ER) from an oestrogen-independent subclone of the MCF-7 human breast cancer cell line. This receptor contains an in-frame, tandem duplication of exons 6 and 7, located in the steroid-binding domain of the ER. This mutation has abrogated l...

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Detalles Bibliográficos
Autores principales: Pink, J. J., Fritsch, M., Bilimoria, M. M., Assikis, V. J., Jordan, V. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222702/
https://www.ncbi.nlm.nih.gov/pubmed/9000593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222702/
https://www.ncbi.nlm.nih.gov/pubmed/9000593

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