Comparative pharmacokinetic and cytotoxic analysis of three different formulations of mitoxantrone in mice.

Two liposomal formulations of mitoxantrone (MTO) were compared with the aqueous solution (free MTO) in terms of their pharmacokinetic behaviour in ICR mice and cytotoxic activity in a nude mouse xenograft model. The three different formulations of MTO [free MTO, phosphatidic acid (PA)-MTO liposomes,...

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Detalles Bibliográficos
Autores principales: Rentsch, K. M., Horber, D. H., Schwendener, R. A., Wunderli-Allenspach, H., Hänseler, E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222749/
https://www.ncbi.nlm.nih.gov/pubmed/9083333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222749/
https://www.ncbi.nlm.nih.gov/pubmed/9083333

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