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Activation and Two Modes of Blockade by Strontium of Ca(2+)-activated K(+) Channels in Goldfish Saccular Hair Cells

Effects of internal Sr(2+) on the activity of large-conductance Ca(2+)-activated K(+) channels were studied in inside-out membrane patches from goldfish saccular hair cells. Sr(2+) was approximately one-fourth as potent as Ca(2+) in activating these channels. Although the Hill coefficient for Sr(2+)...

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Detalles Bibliográficos
Autor principal: Sugihara, Izumi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222763/
https://www.ncbi.nlm.nih.gov/pubmed/9450948