Cargando…

K-ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small-cell lung cancer.

We examined 159 consecutive cases of non-small-cell lung cancer (NSCLC) for a mutation at codon 12 of the K-ras gene and for a mutation of the p53 gene occurring in exons 5-8. Eleven (6.9%) had mutations of the K-ras (ras+) and 57 (35.8%) had mutations of the p53 (p53+). There were 95 cases (59.7%)...

Descripción completa

Detalles Bibliográficos
Autores principales: Fukuyama, Y., Mitsudomi, T., Sugio, K., Ishida, T., Akazawa, K., Sugimachi, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222780/
https://www.ncbi.nlm.nih.gov/pubmed/9099959