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Loss of heterozygosity at the 5,10-methylenetetrahydrofolate reductase locus in human ovarian carcinomas.

The high-affinity folate-binding protein (FBP) is primarily involved in the uptake of the 5-methyltetrahydrofolate, and its expression may be physiologically regulated by the intracellular folate content. The overexpression of FBP on the cell surface of ovarian carcinoma cells may be responsible for...

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Detalles Bibliográficos
Autores principales: Viel, A., Dall'Agnese, L., Simone, F., Canzonieri, V., Capozzi, E., Visentin, M. C., Valle, R., Boiocchi, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222800/
https://www.ncbi.nlm.nih.gov/pubmed/9099956