Cargando…

The β Subunit Increases the Ca(2+) Sensitivity of Large Conductance Ca(2+)-activated Potassium Channels by Retaining the Gating in the Bursting States

Coexpression of the β subunit (K(V),(Ca)β) with the α subunit of mammalian large conductance Ca(2+)- activated K(+) (BK) channels greatly increases the apparent Ca(2+) sensitivity of the channel. Using single-channel analysis to investigate the mechanism for this increase, we found that the β subuni...

Descripción completa

Detalles Bibliográficos
Autores principales: Nimigean, Crina M., Magleby, Karl L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222905/
https://www.ncbi.nlm.nih.gov/pubmed/10051518