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The β Subunit Increases the Ca(2+) Sensitivity of Large Conductance Ca(2+)-activated Potassium Channels by Retaining the Gating in the Bursting States
Coexpression of the β subunit (K(V),(Ca)β) with the α subunit of mammalian large conductance Ca(2+)- activated K(+) (BK) channels greatly increases the apparent Ca(2+) sensitivity of the channel. Using single-channel analysis to investigate the mechanism for this increase, we found that the β subuni...
Autores principales: | Nimigean, Crina M., Magleby, Karl L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222905/ https://www.ncbi.nlm.nih.gov/pubmed/10051518 |
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