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Mechanism of Allosteric Modulation of Rod Cyclic Nucleotide–gated Channels

The cyclic nucleotide–gated (CNG) channel of retinal rod photoreceptor cells is an allosteric protein whose activation is coupled to a conformational change in the ligand-binding site. The bovine rod CNG channel can be activated by a number of different agonists, including cGMP, cIMP, and cAMP. Thes...

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Detalles Bibliográficos
Autores principales: Sunderman, Elizabeth R., Zagotta, William N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222912/
https://www.ncbi.nlm.nih.gov/pubmed/10228178