Notch Signalling Synchronizes the Zebrafish Segmentation Clock but Is Not Needed To Create Somite Boundaries

Somite segmentation depends on a gene expression oscillator or clock in the posterior presomitic mesoderm (PSM) and on read-out machinery in the anterior PSM to convert the pattern of clock phases into a somite pattern. Notch pathway mutations disrupt somitogenesis, and previous studies have suggest...

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Detalles Bibliográficos
Autores principales: Özbudak, Ertuğrul M, Lewis, Julian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222926/
https://www.ncbi.nlm.nih.gov/pubmed/18248098
http://dx.doi.org/10.1371/journal.pgen.0040015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222926/
https://www.ncbi.nlm.nih.gov/pubmed/18248098
http://dx.doi.org/10.1371/journal.pgen.0040015

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