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Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking

BACKGROUND: Age-related macular degeneration (AMD) is the major cause of blindness in the elderly. Those with the neovascular end-stage of disease have irreversible loss of central vision. AMD is a complex disorder in which genetic and environmental factors play a role. Polymorphisms in the compleme...

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Detalles Bibliográficos
Autores principales: Hughes, Anne E, Orr, Nick, Patterson, Chris, Esfandiary, Hossein, Hogg, Ruth, McConnell, Vivienne, Silvestri, Giuliana, Chakravarthy, Usha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222948/
https://www.ncbi.nlm.nih.gov/pubmed/18162041
http://dx.doi.org/10.1371/journal.pmed.0040355