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Persistent Coxiella burnetii Infection in Mice Overexpressing IL-10: An Efficient Model for Chronic Q Fever Pathogenesis

Interleukin (IL)-10 increases host susceptibility to microorganisms and is involved in intracellular persistence of bacterial pathogens. IL-10 is associated with chronic Q fever, an infectious disease due to the intracellular bacterium Coxiella burnetii. Nevertheless, accurate animal models of chron...

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Detalles Bibliográficos
Autores principales: Meghari, Soraya, Bechah, Yassina, Capo, Christian, Lepidi, Hubert, Raoult, Didier, Murray, Peter J, Mege, Jean-Louis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222951/
https://www.ncbi.nlm.nih.gov/pubmed/18248094
http://dx.doi.org/10.1371/journal.ppat.0040023