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GATA3-Driven Th2 Responses Inhibit TGF-β1–Induced FOXP3 Expression and the Formation of Regulatory T Cells
Transcription factors act in concert to induce lineage commitment towards Th1, Th2, or T regulatory (T(reg)) cells, and their counter-regulatory mechanisms were shown to be critical for polarization between Th1 and Th2 phenotypes. FOXP3 is an essential transcription factor for natural, thymus-derive...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222968/ https://www.ncbi.nlm.nih.gov/pubmed/18162042 http://dx.doi.org/10.1371/journal.pbio.0050329 |