Cargando…

A Tertiary Twist to the Transglutaminase Tale

A novel structure shows tissue transglutaminase in its catalytically active form, revealing the mode of action of this crosslinking enzyme and facilitating the development of specific inhibitors for use in various diseases in which transglutaminases are implicated.

Detalles Bibliográficos
Autor principal: Koning, Frits
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222976/
https://www.ncbi.nlm.nih.gov/pubmed/18162046
http://dx.doi.org/10.1371/journal.pbio.0050337