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Analysis of the Human Kinome Using Methods Including Fold Recognition Reveals Two Novel Kinases
BACKGROUND: Protein sequence similarity is a commonly used criterion for inferring the unknown function of a protein from a protein of known function. However, proteins can diverge significantly over time such that sequence similarity is difficult, if not impossible, to find. In some cases, a struct...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223070/ https://www.ncbi.nlm.nih.gov/pubmed/18270584 http://dx.doi.org/10.1371/journal.pone.0001597 |