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Unitary Ca(2+) Current through Cardiac Ryanodine Receptor Channels under Quasi-Physiological Ionic Conditions

Single canine cardiac ryanodine receptor channels were incorporated into planar lipid bilayers. Single-channel currents were sampled at 1–5 kHz and filtered at 0.2–1.0 kHz. Channel incorporations were obtained in symmetrical solutions (20 mM HEPES-Tris, pH 7.4, and pCa 5). Unitary Ca(2+) currents we...

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Detalles Bibliográficos
Autores principales: Mejía-Alvarez, Rafael, Kettlun, Claudia, Ríos, Eduardo, Stern, Michael, Fill, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223367/
https://www.ncbi.nlm.nih.gov/pubmed/9925817