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Active Nuclear Import and Export Is Independent of Lumenal Ca(2+) Stores in Intact Mammalian Cells

The nuclear pore complex (NPC) mediates communication between the cytoplasm and nucleus in eukaryotic cells. Active transport of large polypeptides as well as passive diffusion of smaller (≈10 kD) macromolecules through the NPC can be inhibited by depletion of intracellular Ca(2+) stores. However, t...

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Detalles Bibliográficos
Autores principales: Strübing, Carsten, Clapham, David E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223372/
https://www.ncbi.nlm.nih.gov/pubmed/9925822