Influence of single and multiple doses of amifostine on the efficacy and the pharmacokinetics of carboplatin in mice.

We have previously reported that amifostine potentiates the anti-tumour activity of carboplatin in mice. The present study was carried out in well-established human ovarian cancer xenografts OVCAR-3, A2780 and FMa grown subcutaneously in the nude mouse. It was found that a single dose of amifostine...

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Detalles Bibliográficos
Autores principales: Korst, A. E., Boven, E., van der Sterre, M. L., Fichtinger-Schepman, A. M., van der Vijgh, W. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223489/
https://www.ncbi.nlm.nih.gov/pubmed/9166935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223489/
https://www.ncbi.nlm.nih.gov/pubmed/9166935

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