Growth of methionine-dependent human prostate cancer (PC-3) is inhibited by ethionine combined with methionine starvation.

Methionine (MET) is required for cell metabolism. MET endogenously synthesized from homocysteine (HCY) supports the proliferation of normal cells, but not that of numerous malignant cells, as shown previously. MET starvation should have an anti-tumour effect, and its deleterious effects on the hosts...

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Detalles Bibliográficos
Autores principales: Poirson-Bichat, F., Gonfalone, G., Bras-Gonçalves, R. A., Dutrillaux, B., Poupon, M. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223532/
https://www.ncbi.nlm.nih.gov/pubmed/9184175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223532/
https://www.ncbi.nlm.nih.gov/pubmed/9184175

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