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Mechanism of hyperthermic potentiation of cisplatin action in cisplatin-sensitive and -resistant tumour cells.

In this study, the mechanism(s) by which heat increases cis-diamminedichloroplatinum (cisplatin, cDDP) sensitivity in cDDP-sensitive and -resistant cell lines of murine as well as human origin were investigated. Heating cells at 43 degrees C during cDDP exposure was found to increase drug accumulati...

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Detalles Bibliográficos
Autores principales: Hettinga, J. V., Lemstra, W., Meijer, C., Dam, W. A., Uges, D. R., Konings, A. W., De Vries, E. G., Kampinga, H. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223603/
https://www.ncbi.nlm.nih.gov/pubmed/9192975