Nuclear accumulation of p53 correlates significantly with clinical features and inversely with the expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) in pancreatic cancer.

Recent studies have suggested a p53-independent expression of p21(WAF1/CIP1). We investigated the correlation between p53 overexpression and the expression of p21(WAF1/CIP1) in 57 patients with pancreatic adenocarcinoma. By means of reverse transcription and polymerase chain reaction (RT-PCR), we ex...

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Detalles Bibliográficos
Autores principales: Harada, N., Gansauge, S., Gansauge, F., Gause, H., Shimoyama, S., Imaizumi, T., Mattfeld, T., Schoenberg, M. H., Beger, H. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224055/
https://www.ncbi.nlm.nih.gov/pubmed/9252195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224055/
https://www.ncbi.nlm.nih.gov/pubmed/9252195

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