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ACTION OF MITOCHONDRIAL DNAASE I IN DESTROYING THE CAPACITY OF ISOLATED CELL NUCLEI TO FORM GELS

1. DNA prepared from non-gelable rat liver nuclei isolated in the presence of disrupted mitochondria at pH 6.0, has been compared with DNA obtained from gelable nuclei isolated at pH 4.0. The DNA of the non-gelable nuclei is partially depolymerized relative to the DNA of the gelable nuclei. 2. It ha...

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Detalles Bibliográficos
Autores principales: Dounce, Alexander L., O'Connell, Marguerite P., Monty, Kenneth J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1957
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224124/
https://www.ncbi.nlm.nih.gov/pubmed/13475382