Cargando…

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

BACKGROUND: CCR5-restricted (R5) human immunodeficiency virus type 1 (HIV-1) variants cause CD4+ T-cell loss in the majority of individuals who progress to AIDS, but mechanisms underlying the pathogenicity of R5 strains are poorly understood. To better understand envelope glycoprotein (Env) determin...

Descripción completa

Detalles Bibliográficos
Autores principales: Sterjovski, Jasminka, Churchill, Melissa J, Ellett, Anne, Gray, Lachlan R, Roche, Michael J, Dunfee, Rebecca L, Purcell, Damian FJ, Saksena, Nitin, Wang, Bin, Sonza, Secondo, Wesselingh, Steven L, Karlsson, Ingrid, Fenyo, Eva-Maria, Gabuzda, Dana, Cunningham, Anthony L, Gorry, Paul R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225424/
https://www.ncbi.nlm.nih.gov/pubmed/18076768
http://dx.doi.org/10.1186/1742-4690-4-89