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Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella

BACKGROUND: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we describe a general method that can improve microarray analysis of toxicant-exposed cells that uses the intrinsic power o...

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Detalles Bibliográficos
Autores principales: Ward, William O, Swartz, Carol D, Porwollik, Steffen, Warren, Sarah H, Hanley, Nancy M, Knapp, Geremy W, McClelland, Michael, DeMarini, David M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225428/
https://www.ncbi.nlm.nih.gov/pubmed/17925033
http://dx.doi.org/10.1186/1471-2105-8-378