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Prevention of Rectal SHIV Transmission in Macaques by Daily or Intermittent Prophylaxis with Emtricitabine and Tenofovir

BACKGROUND: In the absence of an effective vaccine, HIV continues to spread globally, emphasizing the need for novel strategies to limit its transmission. Pre-exposure prophylaxis (PrEP) with antiretroviral drugs could prove to be an effective intervention strategy if highly efficacious and cost-eff...

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Detalles Bibliográficos
Autores principales: García-Lerma, J. Gerardo, Otten, Ron A, Qari, Shoukat H, Jackson, Eddie, Cong, Mian-er, Masciotra, Silvina, Luo, Wei, Kim, Caryn, Adams, Debra R, Monsour, Michael, Lipscomb, Jonathan, Johnson, Jeffrey A, Delinsky, David, Schinazi, Raymond F, Janssen, Robert, Folks, Thomas M, Heneine, Walid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225435/
https://www.ncbi.nlm.nih.gov/pubmed/18254653
http://dx.doi.org/10.1371/journal.pmed.0050028