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Potassium-dependent Changes in the Conformation of the Kv2.1 Potassium Channel Pore
The voltage-gated K(+) channel, Kv2.1, conducts Na(+) in the absence of K(+). External tetraethylammonium (TEA(o)) blocks K(+) currents through Kv2.1 with an IC(50) of 5 mM, but is completely without effect in the absence of K(+). TEA(o) block can be titrated back upon addition of low [K(+)]. This s...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225608/ https://www.ncbi.nlm.nih.gov/pubmed/10352033 |