Regulation of Type 1 Inositol 1,4,5-Trisphosphate–gated Calcium Channels by InsP(3 )and Calcium : Simulation of Single Channel Kinetics Based on Ligand Binding and Electrophysiological Analysis

Cytosolic calcium acts as both a coagonist and an inhibitor of the type 1 inositol 1,4,5-trisphosphate (InsP(3))–gated Ca channel, resulting in a bell-shaped Ca dependence of channel activity (Bezprozvanny, I., J. Watras, and B.E. Ehrlich. 1991. Nature. 351:751–754; Finch, E.A., T.J. Turner, and S.M...

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Detalles Bibliográficos
Autores principales: Moraru, I.I., Kaftan, E.J., Ehrlich, B.E., Watras, J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225610/
https://www.ncbi.nlm.nih.gov/pubmed/10352034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225610/
https://www.ncbi.nlm.nih.gov/pubmed/10352034

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