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Structure-Activity Relationships of Several Cardiotonic Steroids with Respect to Inhibition of Ion Transport in Frog Muscle

Cesium uptake by sodium-loaded frog sartorius muscles was inhibited 100% by 10(-6) M ouabain and 10(-6) M cymarin. The doses for 50% inhibition of cesium uptake by five cardiotonic aglycones were 1.5 x 10(-6) M for strophanthidin, 2 x 10(-7) M for telocinobufagin, 1.6 x 10(-6) for digitoxigenin, 2.4...

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Detalles Bibliográficos
Autor principal: Abeles, A. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1969
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225921/
https://www.ncbi.nlm.nih.gov/pubmed/5796371