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NF-κB-dependent synergistic regulation of CXCL10 gene expression by IL-1β and IFN-γ in human intestinal epithelial cell lines

BACKGROUND AND AIMS: Little is known about the intestinal epithelial expression and secretion of CXCL10 (IP-10), a chemokine involved in recruiting T cells and monocytes. We aimed to study CXCL10 gene expression and regulation by the pro-inflammatory cytokines interleukin (IL)-1β, interferon (IFN)-γ...

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Detalles Bibliográficos
Autores principales: Yeruva, Sunil, Ramadori, Giuliano, Raddatz, Dirk
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225996/
https://www.ncbi.nlm.nih.gov/pubmed/18046562
http://dx.doi.org/10.1007/s00384-007-0396-6