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The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine
The inhibition of sodium currents by quaternary derivatives of lidocaine was studied in single myelinated nerve fibers. Membrane currents were diminished little by external quaternary lidocaine (QX). QX present in the axoplasm (<0.5 mM) inhibited sodium currents by more than 90%. Inhibition occur...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1973
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226105/ https://www.ncbi.nlm.nih.gov/pubmed/4541340 |