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The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine

The inhibition of sodium currents by quaternary derivatives of lidocaine was studied in single myelinated nerve fibers. Membrane currents were diminished little by external quaternary lidocaine (QX). QX present in the axoplasm (<0.5 mM) inhibited sodium currents by more than 90%. Inhibition occur...

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Detalles Bibliográficos
Autor principal: Strichartz, Gary R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226105/
https://www.ncbi.nlm.nih.gov/pubmed/4541340