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Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors

BACKGROUND: Urothelial carcinoma (UC) is characterized by nonrandom chromosomal aberrations, varying from one or a few changes in early-stage and low-grade tumors, to highly rearranged karyotypes in muscle-invasive lesions. Recent array-CGH analyses have shed further light on the genomic changes und...

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Detalles Bibliográficos
Autores principales: Heidenblad, Markus, Lindgren, David, Jonson, Tord, Liedberg, Fredrik, Veerla, Srinivas, Chebil, Gunilla, Gudjonsson, Sigurdur, Borg, Åke, Månsson, Wiking, Höglund, Mattias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2227947/
https://www.ncbi.nlm.nih.gov/pubmed/18237450
http://dx.doi.org/10.1186/1755-8794-1-3