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Confocal microscopy visualization of antifolate uptake by the reduced folate carrier in human leukaemic cells.

Confocal microscopy was used to visualize the intracellular uptake of the fluorescent methotrexate analogue, fluorescein-MTX (F-MTX), in human leukaemic cell lines and leukaemic blasts. Cytosolic labelling of wild-type K562 human erythroleukaemia cells was detected during 3-60 min incubations with F...

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Detalles Bibliográficos
Autores principales: Jolivet, J., Faure, M. P., Wong, S. C., Taub, J. W., Matherly, L. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228032/
https://www.ncbi.nlm.nih.gov/pubmed/9310238