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Methylation similarities of two CpG sites within exon 5 of human H19 between normal tissues and testicular germ cell tumours of adolescents and adults, without correlation with allelic and total level of expression.

Testicular germ cell tumours (TGCTs) of adolescents and adults morphologically mimic different stages of embryogenesis. Established cell lines of these cancers are used as informative models to study early development. We found that, in contrast to normal development, TGCTs show a consistent biallel...

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Detalles Bibliográficos
Autores principales: Gillis, A. J., Verkerk, A. J., Dekker, M. C., van Gurp, R. J., Oosterhuis, J. W., Looijenga, L. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228033/
https://www.ncbi.nlm.nih.gov/pubmed/9310237