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The bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitor.

Topoisomerase I inhibitors are new compounds of interest for cancer chemotherapy. We performed a study with GI147211, a new semisynthetic camptothecin analogue, to determine the absolute bioavailability of the drug given orally. Patients with a histologically confirmed diagnosis of a solid tumour re...

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Detalles Bibliográficos
Autores principales: Gerrits, C. J., Schellens, J. H., Creemers, G. J., Wissel, P., Planting, A. S., Pritchard, J. F., DePee, S., de Boer-Dennert, M., Harteveld, M., Verweij, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228077/
https://www.ncbi.nlm.nih.gov/pubmed/9328158