Similarity of apoptosis induction by 2-chlorodeoxyadenosine and cisplatin in human mononuclear blood cells.

The purine analogue 2-chlorodeoxyadenosine (CdA) is unique compared with traditional antimetabolite drugs, as it has shown equal activity in dividing and resting lymphocytes. Poly(ADP-ribose)polymerase (PARP) activation and consecutive NAD+ consumption have been associated with the induction of apop...

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Detalles Bibliográficos
Autores principales: Borner, M. M., Joncourt, F., Hotz, M. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228169/
https://www.ncbi.nlm.nih.gov/pubmed/9400941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228169/
https://www.ncbi.nlm.nih.gov/pubmed/9400941

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