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Similarity of apoptosis induction by 2-chlorodeoxyadenosine and cisplatin in human mononuclear blood cells.
The purine analogue 2-chlorodeoxyadenosine (CdA) is unique compared with traditional antimetabolite drugs, as it has shown equal activity in dividing and resting lymphocytes. Poly(ADP-ribose)polymerase (PARP) activation and consecutive NAD+ consumption have been associated with the induction of apop...
Autores principales: | Borner, M. M., Joncourt, F., Hotz, M. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228169/ https://www.ncbi.nlm.nih.gov/pubmed/9400941 |
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