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A phase I/II study of a hypoxic cell radiosensitizer KU-2285 in combination with intraoperative radiotherapy.

A fluorinated 2-nitroimidazole radiosensitizer KU-2285 was given before intraoperative radiotherapy (IORT) to 30 patients with unresectable, unresected or macroscopic residual tumours. Twenty-three patients had pancreatic cancer and five had osteosarcoma. The IORT dose was 30 Gy for unresectable pan...

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Detalles Bibliográficos
Autores principales: Shibamoto, Y., Ohshio, G., Hosotani, R., Nishimura, Y., Manabe, T., Imamura, M., Abe, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228186/
https://www.ncbi.nlm.nih.gov/pubmed/9400944