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Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors

BACKGROUND: Animal and clinical studies have revealed that focal peripheral nerve axon demyelination is accompanied by nociceptive pain behavior. C-C and C-X-C chemokines and their receptors have been strongly implicated in demyelinating polyneuropathies and persistent pain syndromes. Herein, we stu...

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Detalles Bibliográficos
Autores principales: Bhangoo, Sonia, Ren, Dongjun, Miller, Richard J, Henry, Kenneth J, Lineswala, Jayana, Hamdouchi, Chafiq, Li, Baolin, Monahan, Patrick E, Chan, David M, Ripsch, Matthew S, White, Fletcher A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228278/
https://www.ncbi.nlm.nih.gov/pubmed/18076762
http://dx.doi.org/10.1186/1744-8069-3-38