Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase

BACKGROUND: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (EC 2.4.2.8) is a central enzyme in the purine recycling pathway. Parasitic protozoa of the order Kinetoplastida cannot synthesize purines de novo and use the salvage pathway to synthesize purine bases, making this an attractive targ...

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Detalles Bibliográficos
Autores principales: Monzani, Paulo S, Trapani, Stefano, Thiemann, Otavio H, Oliva, Glaucius
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228302/
https://www.ncbi.nlm.nih.gov/pubmed/17894860
http://dx.doi.org/10.1186/1472-6807-7-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228302/
https://www.ncbi.nlm.nih.gov/pubmed/17894860
http://dx.doi.org/10.1186/1472-6807-7-59

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