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Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites

BACKGROUND: The antimalarial drug atovaquone specifically targets Plasmodium falciparum cytochrome b (Pfcytb), a mitochondrial gene with uniparental inheritance. Cases of resistance to atovaquone associated with mutant Pfcytb have been reported, justifying efforts to better document the natural poly...

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Detalles Bibliográficos
Autores principales: Ekala, Marie-Thérèse, Khim, Nimol, Legrand, Eric, Randrianarivelojosia, Milijaona, Jambou, Ronan, Fandeur, Thierry, Menard, Didier, Assi, Serge-Brice, Henry, Marie-Claire, Rogier, Christophe, Bouchier, Christiane, Mercereau-Puijalon, Odile
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228307/
https://www.ncbi.nlm.nih.gov/pubmed/18086297
http://dx.doi.org/10.1186/1475-2875-6-164