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Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites
BACKGROUND: The antimalarial drug atovaquone specifically targets Plasmodium falciparum cytochrome b (Pfcytb), a mitochondrial gene with uniparental inheritance. Cases of resistance to atovaquone associated with mutant Pfcytb have been reported, justifying efforts to better document the natural poly...
Autores principales: | Ekala, Marie-Thérèse, Khim, Nimol, Legrand, Eric, Randrianarivelojosia, Milijaona, Jambou, Ronan, Fandeur, Thierry, Menard, Didier, Assi, Serge-Brice, Henry, Marie-Claire, Rogier, Christophe, Bouchier, Christiane, Mercereau-Puijalon, Odile |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228307/ https://www.ncbi.nlm.nih.gov/pubmed/18086297 http://dx.doi.org/10.1186/1475-2875-6-164 |
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