Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA

Formation and fragmentation of recognition complexes between trioxacarcin A and various DNA sequences were examined by temperature-dependent UV and CD spectroscopy, HPLC analysis, and ESI mass spectrometry with regard to reaction conditions, intermediates, products, mechanism, and sequence specifici...

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Detalles Bibliográficos
Autores principales: Fitzner, Ansgar, Frauendorf, Holm, Laatsch, Hartmut, Diederichsen, Ulf
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228378/
https://www.ncbi.nlm.nih.gov/pubmed/18210096
http://dx.doi.org/10.1007/s00216-007-1737-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228378/
https://www.ncbi.nlm.nih.gov/pubmed/18210096
http://dx.doi.org/10.1007/s00216-007-1737-6

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