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Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA
Formation and fragmentation of recognition complexes between trioxacarcin A and various DNA sequences were examined by temperature-dependent UV and CD spectroscopy, HPLC analysis, and ESI mass spectrometry with regard to reaction conditions, intermediates, products, mechanism, and sequence specifici...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228378/ https://www.ncbi.nlm.nih.gov/pubmed/18210096 http://dx.doi.org/10.1007/s00216-007-1737-6 |