5′ flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasites

In the human malaria parasite Plasmodium falciparum antigenic variation facilitates long-term chronic infection of the host. This is achieved by sequential expression of a single member of the 60-member var family. Here we show that the 5′ flanking region nucleates epigenetic events strongly linked...

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Detalles Bibliográficos
Autores principales: Lopez-Rubio, Jose Juan, Gontijo, Alisson M, Nunes, Marta C, Issar, Neha, Hernandez Rivas, Rosaura, Scherf, Artur
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228885/
https://www.ncbi.nlm.nih.gov/pubmed/18028313
http://dx.doi.org/10.1111/j.1365-2958.2007.06009.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228885/
https://www.ncbi.nlm.nih.gov/pubmed/18028313
http://dx.doi.org/10.1111/j.1365-2958.2007.06009.x

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