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Anomalous Effect of Permeant Ion Concentration on Peak Open Probability of Cardiac Na(+) Channels

Human heart Na(+) channels were expressed transiently in both mammalian cells and Xenopus oocytes, and Na(+) currents measured using 150 mM intracellular Na(+). Decreasing extracellular permeant ion concentration decreases outward Na(+) current at positive voltages while increasing the driving force...

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Detalles Bibliográficos
Autores principales: Townsend, Claire, Hartmann, Hali A., Horn, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229355/
https://www.ncbi.nlm.nih.gov/pubmed/9234167