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Effect of Alkali Metal Cations on Slow Inactivation of Cardiac Na(+) Channels

Human heart Na(+) channels were expressed transiently in both mammalian cells and Xenopus oocytes, and Na(+) currents measured using 150 mM intracellular Na(+). The kinetics of decaying outward Na(+) current in response to 1-s depolarizations in the F1485Q mutant depends on the predominant cation in...

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Detalles Bibliográficos
Autores principales: Townsend, Claire, Horn, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229358/
https://www.ncbi.nlm.nih.gov/pubmed/9234168