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Correlation between Charge Movement and Ionic Current during Slow Inactivation in Shaker K(+) Channels

Prolonged depolarization induces a slow inactivation process in some K(+) channels. We have studied ionic and gating currents during long depolarizations in the mutant Shaker H4-Δ(6–46) K(+) channel and in the nonconducting mutant (Shaker H4-Δ(6–46)-W434F). These channels lack the amino terminus tha...

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Detalles Bibliográficos
Autores principales: Olcese, Riccardo, Latorre, Ramón, Toro, Ligia, Bezanilla, Francisco, Stefani, Enrico
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229383/
https://www.ncbi.nlm.nih.gov/pubmed/9348329