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Interactions between Multiple Phosphorylation Sites in the Inactivation Particle of a K(+) Channel : Insights into the Molecular Mechanism of Protein Kinase C Action
Protein kinase C inhibits inactivation gating of Kv3.4 K(+) channels, and at least two NH(2)-terminal serines (S15 and S21) appeared involved in this interaction (Covarrubias et al. 1994. Neuron. 13:1403–1412). Here we have investigated the molecular mechanism of this regulatory process. Site-direct...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229409/ https://www.ncbi.nlm.nih.gov/pubmed/9649584 |