Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification

ATP-sensitive potassium (K(ATP)) channels are reversibly inhibited by intracellular ATP. Agents that interact with sulfhydryl moieties produce an irreversible inhibition of K(ATP) channel activity when applied to the intracellular membrane surface. ATP appears to protect against this effect, suggest...

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Detalles Bibliográficos
Autores principales: Trapp, Stefan, Tucker, Stephen J., Ashcroft, Frances M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229416/
https://www.ncbi.nlm.nih.gov/pubmed/9725892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229416/
https://www.ncbi.nlm.nih.gov/pubmed/9725892

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