The Diphtheria Toxin Channel-forming T Domain Translocates Its Own NH(2)-Terminal Region Across Planar Bilayers

The T domain of diphtheria toxin, which extends from residue 202 to 378, causes the translocation of the catalytic A fragment (residues 1–201) across endosomal membranes and also forms ion-conducting channels in planar phospholipid bilayers. The carboxy terminal 57-amino acid segment (322–378) in th...

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Detalles Bibliográficos
Autores principales: Senzel, Lisa, Huynh, Paul D., Jakes, Karen S., John Collier, R., Finkelstein, Alan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229418/
https://www.ncbi.nlm.nih.gov/pubmed/9725891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229418/
https://www.ncbi.nlm.nih.gov/pubmed/9725891

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