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The Diphtheria Toxin Channel-forming T Domain Translocates Its Own NH(2)-Terminal Region Across Planar Bilayers

The T domain of diphtheria toxin, which extends from residue 202 to 378, causes the translocation of the catalytic A fragment (residues 1–201) across endosomal membranes and also forms ion-conducting channels in planar phospholipid bilayers. The carboxy terminal 57-amino acid segment (322–378) in th...

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Detalles Bibliográficos
Autores principales:	Senzel, Lisa, Huynh, Paul D., Jakes, Karen S., John Collier, R., Finkelstein, Alan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229418/ https://www.ncbi.nlm.nih.gov/pubmed/9725891

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